Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7689792 | 0.88 | HDAC6 (0.37) | NPC1GAAHDAC6NR1H4PPARG | |
| SCHEMBL3297999 | 0.87 | KDM4E (0.44) | NPC1RAB9ALMNAGAAPPARG | |
| SCHEMBL30929993 | 0.84 | ALDH1A1 (0.36) | NPC1RAB9ALMNAGAAPOLB | |
| SCHEMBL8835025 | 0.79 | NR1H4 (0.37) | NPC1RAB9AGAAHDAC6NR1H4 | |
| SCHEMBL7199140 | 0.79 | PPARG (0.44) | NPC1RAB9AGAAHDAC6NR1H4 | |
| SCHEMBL29768287 | 0.79 | MAOB (0.45) | NPC1RAB9ALMNAGAAPOLB | |
| SCHEMBL100766 | 0.79 | MAOB (0.45) | NPC1RAB9ALMNAGAAPOLB | |
| SCHEMBL8362661 | 0.79 | NR1H4 (0.44) | NPC1RAB9ALMNAHDAC6NR1H4 | |
| SCHEMBL8640100 | 0.77 | NR1H4 (0.42) | NPC1RAB9ALMNAGAAHDAC6 | |
| SCHEMBL29213557 | 0.76 | MAOB (0.40) | NPC1RAB9ALMNAGAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002079173-A1 | BENZOTRIAZOLES AND THEIR USE AS UV LIGHT STABILISERS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2002-10-10 | — | — | WO | claimed |