SCHEMBL769622

SCHEMBL769622

C[C@@H](O)[C@H](NOP(=O)=O)C(=O)O

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.35
CA2 P00918 2/20 0.32
CA1 P00915 1/20 0.32
PDCD1LG2 Q9BQ51 1/20 0.31
CD274 Q9NZQ7 1/20 0.31
MME P08473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15373625 0.76 TP53 (0.39) TP53CA2CA1MME
SCHEMBL42676 0.71 TP53 (0.39) TP53CA2CA1MME
SCHEMBL27906144 0.71 ALDH1A1 (0.36) TP53CA2CA1PDCD1LG2CD274
SCHEMBL10722578 0.71 TP53 (0.35) TP53CA2CA1MME
Bicarbonate SCHEMBL28006549 0.70 TP53 (0.38) TP53CA2CA1MME
SCHEMBL27534148 0.70 TP53 (0.38) TP53CA2CA1MME
SCHEMBL2510065 0.69 PGK1 (0.35) TP53CA2CA1MME
SCHEMBL769620 0.69 PGK1 (0.35) TP53CA2CA1MME
SCHEMBL29858530 0.69 TP53 (0.47) TP53CA2CA1PDCD1LG2CD274
SCHEMBL14819886 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8168417-B2 Bacillus licheniformis chromosome NOVOZYMES A/S (DK) 2012-05-01 US disclosed
US-20120070881-A1 Bacillus licheniformis chromosome NOVOZYMES A/S (DK) 2012-03-22 US disclosed
US-20110086407-A1 Bacillus licheniformis chromosome NOVOZYMES A/S (DK) 2011-04-14 US disclosed
US-7863032-B2 Bacillus licheniformis chromosome-encoded endoglucanase NOVOZYMES, INC. (US) 2011-01-04 US disclosed
US-20090275104-A1 Bacillus licheniformis chromosone NOVOZYMES A/S (DK) 2009-11-05 US disclosed
US-7494798-B2 Bacillus licheniformis chromosome NOVOZYMES, INC. (US) 2009-02-24 US disclosed
US-20080050774-A1 Computer-based system for monitoring differential expression; host cells NOVOZYMES A/S (DK) 2008-02-28 US disclosed
WO-2002068622-A2 CRYSTAL STRUCTURE INFORMATION OF PNP SYNTHASE AND THE USE THEREOF MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN (DE) 2002-09-06 WO disclosed