SCHEMBL7696241

SCHEMBL7696241

Cc1cc(C)cc(-c2nc3ccc(C(C)(C)C(=O)N4C5CCC4CC5)cn3c2CCNCc2ccc(-c3cccnc3)cc2)c1

nearest known ligand 0.47

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GNRHR P30968 20/20 0.47
CYP3A4 P08684 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7702487 0.92 GNRHR (0.47) GNRHRCYP3A4
SCHEMBL8346371 0.78 GNRHR (0.76) GNRHRCYP3A4
SCHEMBL7698735 0.67 GNRHR (0.60) GNRHR
SCHEMBL8182738 0.66 GNRHR (0.71) GNRHRCYP3A4
SCHEMBL8145820 0.66 GNRHR (0.92) GNRHR
SCHEMBL6981337 0.64 GNRHR (1.00) GNRHR
Hydrochloric Acid SCHEMBL6983627 0.63 GNRHR (0.99) GNRHR
SCHEMBL8184930 0.60 GNRHR (0.77) GNRHRCYP3A4
SCHEMBL12818882 0.59 SLC2A1 (0.61)
SCHEMBL2570995 0.59 LMNA (0.62)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002066477-A2 IMIDAZOPYRIDINES ASTRAZENECA AB (SE) 2002-08-29 WO claimed
WO-2002066477-A2 IMIDAZOPYRIDINES ASTRAZENECA AB (SE) 2002-08-29 WO disclosed