SCHEMBL7698735

SCHEMBL7698735

Cc1cc(C)cc(-c2nc3ccc(C(C)(C)C(=O)N(CC(C)C)CC(C)C)cn3c2CCNCCCCc2ccncc2)c1

nearest known ligand 0.60

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GNRHR P30968 17/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7701566 0.74 GNRHR (0.45) GNRHR
SCHEMBL7702487 0.72 GNRHR (0.47) GNRHR
SCHEMBL8088014 0.71 GNRHR (0.80) GNRHR
SCHEMBL8088012 0.71 GNRHR (0.80) GNRHR
SCHEMBL8079137 0.67 GNRHR (0.61) GNRHR
SCHEMBL7696241 0.67 GNRHR (0.47) GNRHR
SCHEMBL8695273 0.66 GNRHR (1.00) GNRHR
SCHEMBL13124100 0.63 GNRHR (0.45) GNRHR
SCHEMBL11891123 0.61 CACNA1B (0.45) GNRHR
SCHEMBL8600810 0.56 GNRHR (0.81) GNRHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002066477-A2 IMIDAZOPYRIDINES ASTRAZENECA AB (SE) 2002-08-29 WO claimed
WO-2002066477-A2 IMIDAZOPYRIDINES ASTRAZENECA AB (SE) 2002-08-29 WO disclosed