Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.58 |
| ▸ | MAPT | P10636 | 7/20 | 0.58 |
| ▸ | MEN1 | O00255 | 6/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | RPS6KB2 | Q9UBS0 | 3/20 | 0.54 |
| ▸ | PGK1 | P00558 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.50 |
| ▸ | RELA | Q04206 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7697803 | 0.83 | ABCG2 (0.62) | KMT2AMAPTMEN1MAPK1HSD17B10 | |
| SCHEMBL7699357 | 0.83 | KMT2A (0.62) | KMT2AMAPTMEN1MAPK1GAA | |
| SCHEMBL7697753 | 0.76 | RPS6KB2 (0.60) | KMT2AMAPTMEN1MAPK1GAA | |
| SCHEMBL7692003 | 0.74 | RPS6KB2 (0.53) | KMT2AMAPTMEN1MAPK1GAA | |
| SCHEMBL7697776 | 0.74 | RPS6KB2 (0.53) | KMT2AMAPTMEN1MAPK1GAA | |
| SCHEMBL6237742 | 0.74 | RPS6KB2 (0.69) | KMT2AMAPTMEN1GAAHSD17B10 | |
| SCHEMBL14366834 | 0.74 | MEN1 (1.00) | KMT2AMAPTMEN1MAPK1GAA | |
| SCHEMBL4019259 | 0.73 | MAPT (0.54) | KMT2AMAPTMEN1GAAKDM4E | |
| SCHEMBL4019884 | 0.73 | MAPT (0.54) | KMT2AMAPTMEN1GAAKDM4E | |
| SCHEMBL4025568 | 0.73 | MAPT (0.54) | KMT2AMAPTMEN1GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002094796-A2 | BENZO[G]QUINOXALINE DERIVATIVES AS EFFECTIVE COMPOUNDS AGAINST INFECTIOUS DISEASES | AXXIMA PHARMACEUTICALS AG (DE) | 2002-11-28 | — | — | WO | disclosed |