Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 8/20 | 0.62 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.62 |
| ▸ | ABCC1 | P33527 | 4/20 | 0.62 |
| ▸ | RPS6KB2 | Q9UBS0 | 3/20 | 0.59 |
| ▸ | PGK1 | P00558 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | GBA1 | P04062 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7696289 | 0.83 | KMT2A (0.58) | RPS6KB2PGK1KDM4EMAPTALDH1A1 | |
| SCHEMBL7696554 | 0.83 | ABCG2 (0.58) | ABCG2ABCB1ABCC1MAPTKMT2A | |
| SCHEMBL7690215 | 0.80 | RPS6KB2 (0.60) | ABCG2RPS6KB2PGK1KDM4EMAPT | |
| SCHEMBL7695652 | 0.80 | RPS6KB2 (0.60) | ABCG2RPS6KB2PGK1KDM4EMAPT | |
| SCHEMBL7697772 | 0.79 | RPS6KB2 (0.58) | ABCG2ABCB1RPS6KB2KDM4EMAPT | |
| SCHEMBL7696931 | 0.78 | RPS6KB2 (0.55) | ABCG2ABCB1RPS6KB2KDM4EMAPT | |
| SCHEMBL7695845 | 0.78 | RPS6KB2 (0.57) | ABCG2RPS6KB2PGK1KDM4EMAPT | |
| SCHEMBL7697783 | 0.78 | RPS6KB2 (0.57) | ABCG2ABCB1RPS6KB2PGK1KDM4E | |
| SCHEMBL7691382 | 0.78 | ABCG2 (0.61) | ABCG2ABCB1RPS6KB2KDM4EMAPT | |
| SCHEMBL7694559 | 0.76 | RPS6KB2 (0.51) | RPS6KB2PGK1KDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002094796-A2 | BENZO[G]QUINOXALINE DERIVATIVES AS EFFECTIVE COMPOUNDS AGAINST INFECTIOUS DISEASES | AXXIMA PHARMACEUTICALS AG (DE) | 2002-11-28 | — | — | WO | disclosed |