SCHEMBL7696301

SCHEMBL7696301

Nc1ccc(O)cc1OCCO

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.44
HSD17B10 Q99714 2/20 0.44
KDM4E B2RXH2 1/20 0.44
MEN1 O00255 1/20 0.44
POLB P06746 1/20 0.44
MAPT P10636 1/20 0.44
HPGD P15428 1/20 0.44
MAPK1 P28482 1/20 0.44
KMT2A Q03164 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
IDO1 P14902 1/20 0.41
RECQL P46063 1/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
CA14 Q9ULX7 1/20 0.36
ROCK2 O75116 1/20 0.36
ESR2 Q92731 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2026961 0.85 PRSS1 (0.47) ALDH1A1HSD17B10KDM4EMEN1POLB
SCHEMBL23568201 0.84 ALDH1A1 (0.62) ALDH1A1HSD17B10KDM4EMEN1POLB
SCHEMBL9002364 0.83 CA12 (0.39) ALDH1A1HSD17B10KDM4EMEN1POLB
SCHEMBL4389330 0.83 MAPT (0.51) ALDH1A1HSD17B10KDM4EMEN1POLB
SCHEMBL27961434 0.83 ALDH1A1 (0.39) ALDH1A1HSD17B10KDM4EMEN1POLB
SCHEMBL33692 0.82 ALDH1A1 (0.46) ALDH1A1HSD17B10KDM4EMEN1POLB
SCHEMBL29393081 0.82 ALDH1A1 (0.46) ALDH1A1HSD17B10KDM4EMEN1POLB
Hydrochloric Acid SCHEMBL15301977 0.81 MAPT (0.49) ALDH1A1HSD17B10KDM4EMEN1POLB
Hydrochloric Acid SCHEMBL6739541 0.81 MAPT (0.49) ALDH1A1HSD17B10KDM4EMEN1POLB
SCHEMBL7042018 0.81 ALDH1A1 (0.45) ALDH1A1HSD17B10KDM4EMEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0589952-B1 USE OF SUPLHUR METAAMINOPHENOLS FOR DYEING KERATINIC FIBRES, TINCTORIAL COMPOSITIONS AND NOVEL COMPOUNDS OREAL (FR) 1997-08-27 EP claimed
EP-0591373-B1 META-AMINOPHENOLS, THEIR USE AS COUPLERS FOR OXIDATION DYEING OF KERATINOUS FIBRES, DYE COMPOSITIONS AND METHOD OREAL (FR) 1996-05-22 EP claimed
US-5478359-A Applying a hair dyes L'OREAL (FR) 1995-12-26 US claimed
US-5443596-A Keratinous fiber dyeing compositions and processes utilizing oxidation dye precursors in combination with dimethoxy meta-aminophenol couplers L'OREAL (FR) 1995-08-22 US claimed
EP-0591373-A1 META-AMINOPHENOLS, THEIR USE AS COUPLERS FOR OXIDATION DYEING OF KERATINOUS FIBRES, DYE COMPOSITIONS AND METHOD. OREAL (FR) 1994-04-13 EP claimed
EP-0589952-A1 USE OF SUPLHUROUS METAAMINOPHENOLS FOR DYING KERATINIC FIBRES, TINCTORIAL COMPOSITIONS AND NOVEL COMPOUNDS. OREAL (FR) 1994-04-06 EP claimed
EP-0331144-B1 3-SUBSTITUTED PARA-AMINO PHENOLS, PROCESS FOR THEIR PREPARATION, THEIR USE IN DYEING KERATENIC FIBRES AND INTERMEDIATES USED IN THE PREPARATION PROCESS L'OREAL (FR) 1993-06-09 EP claimed
WO-1993000066-A1 META-AMINOPHENOLS, THEIR USE AS COUPLERS FOR OXIDATION DYEING OF KERATINOUS FIBRES, DYE COMPOSITIONS AND METHOD L'OREAL (FR) 1993-01-07 WO claimed
WO-1992022525-A1 USE OF SUPLHUROUS METAAMINOPHENOLS FOR DYING KERATINIC FIBRES, TINCTORIAL COMPOSITIONS AND NOVEL COMPOUNDS L'OREAL (FR) 1992-12-23 WO claimed
JP-1272884-A None JP disclosed
US-6342079-B1 1-(2,5-DIPHENYL)ETHANOL FOR HAIR DYES BRISTOL-MYERS SQUIBB COMPANY 2002-01-29 US disclosed
EP-0656202-B1 Dyeing composition containing sulphurous p-phenylene-diamines, sulphurous p-phenylenediamines and method of preparation OREAL (FR) 1999-05-06 EP disclosed
EP-0591059-B1 Use of sulfur-containing metaphenylenediamines for dyeing keratinic fibers and new sulfur-containing metaphenylenediamines OREAL (FR) 1998-04-15 EP disclosed
US-5710311-A 2-sulphured metaphenylenediamines for dyeing hair L'OREAL (FR) 1998-01-20 US disclosed
WO-1993000066-A1 META-AMINOPHENOLS, THEIR USE AS COUPLERS FOR OXIDATION DYEING OF KERATINOUS FIBRES, DYE COMPOSITIONS AND METHOD L'OREAL (FR) 1993-01-07 WO disclosed
WO-1992022525-A1 USE OF SUPLHUROUS METAAMINOPHENOLS FOR DYING KERATINIC FIBRES, TINCTORIAL COMPOSITIONS AND NOVEL COMPOUNDS L'OREAL (FR) 1992-12-23 WO disclosed
US-5084067-A Indoaniline dyes for hair dyes L'OREAL (FR) 1992-01-28 US disclosed
US-5032137-A Hair dye L'OREAL (FR) 1991-07-16 US disclosed
US-4979961-A p-phenylenediamines, process for preparation thereof, dyeing composition containing them and corresponding dyeing process L'OREAL (FR) 1990-12-25 US disclosed
JP-H01272884-A 3-SUBSTITUTED PARA-AMINOPHENOL, ITS PRODUCTION AND COMPOSITION FOR DYEING KERATINOUS FIBER L'OREAL SA 1989-10-31 JP disclosed