SCHEMBL9002364

SCHEMBL9002364

Nc1ccc(O)cc1OCCCCl

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
CA14 Q9ULX7 1/20 0.39
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
ALDH1A1 P00352 1/20 0.39
POLB P06746 1/20 0.39
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
MAPK1 P28482 1/20 0.39
KMT2A Q03164 1/20 0.39
HSD17B10 Q99714 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
CYP1A2 P05177 2/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
PRSS1 P07477 8/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7696301 0.83 ALDH1A1 (0.44) CA12CA1CA2CA7CA9
SCHEMBL4389330 0.81 MAPT (0.51) KDM4EMEN1ALDH1A1POLBMAPT
SCHEMBL27961434 0.81 ALDH1A1 (0.39) CA12CA1CA2CA7CA9
SCHEMBL16803395 0.80 ROCK2 (0.47) KDM4EALDH1A1CYP1A2CYP2C19CYP2D6
SCHEMBL14784670 0.80 ALDH1A1 (0.39) KDM4EMEN1ALDH1A1POLBMAPT
SCHEMBL16803391 0.77 ROCK2 (0.55) KDM4EALDH1A1MAPK1ROCK2
SCHEMBL14784823 0.77 ALDH1A1 (0.40) KDM4EMEN1ALDH1A1POLBMAPT
SCHEMBL4399411 0.77 ALDH1A1 (0.66) KDM4EMEN1ALDH1A1POLBMAPT
SCHEMBL8791587 0.76 MAOB (0.50) MEN1ALDH1A1POLBMAPTHPGD
SCHEMBL16774897 0.76 XDH (0.51) KDM4EMEN1ALDH1A1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5541299-A Process for the preparation of dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1996-07-30 US disclosed
US-5502171-A Process for the preparation of dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1996-03-26 US disclosed
EP-0446731-B1 Process for the manufacture of azo dyes BAYER AG (DE) 1995-05-03 EP disclosed
EP-0446731-A2 Process for the manufacture of azo dyes BAYER AG (DE) 1991-09-18 EP disclosed