Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | FER | P16591 | 1/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.41 |
| ▸ | FLT4 | P35916 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700999 | 0.92 | MAPT (0.48) | MAPTPOLBGSK3BMAPK1DCLK1 | |
| SCHEMBL7694290 | 0.88 | TACR1 (0.51) | CNR2 | |
| SCHEMBL7701529 | 0.87 | POLB (0.52) | MAPTPOLBMAPK1KDM4EALDH1A1 | |
| SCHEMBL7699884 | 0.86 | HPGD (0.42) | MAPTPOLBMAPK1KDM4EALDH1A1 | |
| SCHEMBL7695429 | 0.86 | ADORA2A (0.39) | GSK3BMAPK1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL7699427 | 0.86 | HTT (0.49) | MAPTPOLBMAPK1KDM4EALDH1A1 | |
| SCHEMBL7694391 | 0.85 | CNR1 (0.46) | PPARGCNR2HDAC4KDM4ECYP1A2 | |
| SCHEMBL7695817 | 0.84 | MAOB (0.42) | MAPTPOLBKDM4EALDH1A1HSD17B10 | |
| SCHEMBL7699604 | 0.84 | MAPT (0.47) | MAPTCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL7695160 | 0.84 | MAPT (0.41) | MAPTMAPK1KDM4EALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |