Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7696355 | 0.87 | MAPT (0.46) | POLBMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL7697933 | 0.83 | POLB (0.50) | POLBFAAHMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL7694290 | 0.82 | TACR1 (0.51) | — | |
| SCHEMBL7700372 | 0.82 | HPGD (0.41) | POLBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL7699427 | 0.80 | HTT (0.49) | POLBMAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL7697065 | 0.80 | FAAH (0.52) | POLBFAAHMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL7700999 | 0.80 | MAPT (0.48) | POLBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL7694391 | 0.79 | CNR1 (0.46) | SMN1; SMN2MEN1KMT2AKDM4EHPGD | |
| SCHEMBL7699884 | 0.78 | HPGD (0.42) | POLBMAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL7695429 | 0.78 | ADORA2A (0.39) | ALDH1A1MEN1KMT2AKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |