Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700011 | 0.93 | HTT (0.53) | HTTPOLBALDH1A1HPGDTP53 | |
| SCHEMBL7695429 | 0.91 | ADORA2A (0.39) | HTTALDH1A1HPGDPDE4BPDE11A | |
| SCHEMBL7696355 | 0.86 | MAPT (0.46) | POLBALDH1A1HPGDCYP1A2CYP3A4 | |
| SCHEMBL7694391 | 0.85 | CNR1 (0.46) | HPGDLMNACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL7699719 | 0.84 | MAPT (0.46) | HTTALDH1A1HPGDTP53LMNA | |
| SCHEMBL7695824 | 0.83 | ALDH1A1 (0.45) | HTTALDH1A1HPGDTP53LMNA | |
| SCHEMBL7699884 | 0.81 | HPGD (0.42) | POLBALDH1A1HPGDTP53LMNA | |
| SCHEMBL7701529 | 0.80 | POLB (0.52) | HTTPOLBALDH1A1HPGDTP53 | |
| SCHEMBL7698104 | 0.79 | MAPT (0.51) | POLBALDH1A1HPGDTP53LMNA | |
| SCHEMBL7701239 | 0.79 | MAPT (0.60) | HTTPOLBALDH1A1HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |