Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | SRC | P12931 | 2/20 | 0.37 |
| ▸ | CD44 | P16070 | 1/20 | 0.36 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1562596 | 0.80 | HSP90AA1 (0.37) | NR4A2TDP1KDM4ECYP3A4ALDH1A1 | |
| SCHEMBL17825675 | 0.79 | LMNA (0.38) | CYP3A4LMNASRCKMT2A | |
| SCHEMBL18691141 | 0.79 | NQO2 (0.39) | NR4A2TDP1KDM4ECYP3A4LMNA | |
| SCHEMBL11637772 | 0.75 | KDM4E (0.50) | NR4A2TDP1KDM4ELMNACD44 | |
| SCHEMBL6537500 | 0.73 | NR4A2 (0.41) | NR4A2TDP1KDM4ECYP3A4LMNA | |
| SCHEMBL7693395 | 0.72 | MEN1 (0.43) | TDP1KDM4ECYP3A4LMNAALDH1A1 | |
| SCHEMBL11638493 | 0.72 | KDM4E (0.55) | NR4A2TDP1KDM4ECYP3A4LMNA | |
| SCHEMBL1577694 | 0.71 | LMNA (0.43) | KDM4ECYP3A4LMNAALDH1A1KMT2A | |
| SCHEMBL1563528 | 0.68 | ELANE (0.44) | KDM4ECYP3A4ALDH1A1 | |
| SCHEMBL31607526 | 0.68 | ELANE (0.44) | KDM4ECYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002026713-A1 | ANTIPARASITIC COMPOUNDS | KING'S COLLEGE LONDON (GB) | 2002-04-04 | — | — | WO | disclosed |