Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.68 |
| ▸ | HPGD | P15428 | 15/20 | 0.61 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.57 |
| ▸ | PIM1 | P11309 | 1/20 | 0.55 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7696596 | 1.00 | CISD1 (0.68) | CISD1HPGDGPR35PIM1PIM2 | |
| SCHEMBL7700243 | 0.92 | MYC (0.60) | CISD1HPGDPTGS2 | |
| SCHEMBL7700244 | 0.92 | MYC (0.60) | CISD1HPGDPTGS2 | |
| SCHEMBL212734 | 0.87 | GPR35 (0.70) | CISD1HPGDGPR35PIM1PIM2 | |
| SCHEMBL212733 | 0.87 | GPR35 (0.70) | CISD1HPGDGPR35PIM1PIM2 | |
| SCHEMBL212735 | 0.87 | GPR35 (0.70) | CISD1HPGDGPR35PIM1PIM2 | |
| SCHEMBL22971879 | 0.81 | CISD1 (1.00) | CISD1HPGDPIM1PIM2PTGS2 | |
| SCHEMBL12892082 | 0.81 | HPGD (0.73) | HPGD | |
| SCHEMBL1250092 | 0.81 | HPGD (0.73) | HPGD | |
| SCHEMBL1250091 | 0.81 | HPGD (0.73) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002050024-A2 | THIAZOLIDINEDIONES | SMITHKLINE BEECHAM CORPORATION (US) | 2002-06-27 | — | — | WO | claimed |