Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.60 |
| ▸ | IL1RN | P18510 | 1/20 | 0.60 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.60 |
| ▸ | CISD1 | Q9NZ45 | 3/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.56 |
| ▸ | CTSD | P07339 | 2/20 | 0.56 |
| ▸ | GSK3B | P49841 | 2/20 | 0.55 |
| ▸ | MMP3 | P08254 | 2/20 | 0.53 |
| ▸ | MMP13 | P45452 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | MGAM | O43451 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | SI | P14410 | 1/20 | 0.52 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700243 | 1.00 | MYC (0.60) | MYCIL1RNERAP1CISD1PTGS2 | |
| SCHEMBL7696597 | 0.92 | CISD1 (0.68) | CISD1PTGS2HPGD | |
| SCHEMBL7696596 | 0.92 | CISD1 (0.68) | CISD1PTGS2HPGD | |
| SCHEMBL212734 | 0.79 | GPR35 (0.70) | MYCIL1RNERAP1CISD1PTGS2 | |
| SCHEMBL212733 | 0.79 | GPR35 (0.70) | MYCIL1RNERAP1CISD1PTGS2 | |
| SCHEMBL212735 | 0.79 | GPR35 (0.70) | MYCIL1RNERAP1CISD1PTGS2 | |
| SCHEMBL18102979 | 0.79 | CISD1 (0.66) | CISD1MEN1KMT2AHPGDMGAM | |
| SCHEMBL18102973 | 0.79 | CISD1 (0.66) | CISD1MEN1KMT2AHPGDMGAM | |
| SCHEMBL18102865 | 0.78 | MMP3 (0.65) | MYCIL1RNERAP1PTGS2MEN1 | |
| SCHEMBL10050563 | 0.77 | MMP13 (0.74) | MYCIL1RNERAP1PTGS2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002050024-A2 | THIAZOLIDINEDIONES | SMITHKLINE BEECHAM CORPORATION (US) | 2002-06-27 | — | — | WO | claimed |