⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11986245 | 0.88 | FFAR3 (0.39) | — | |
| SCHEMBL10586224 | 0.88 | FFAR3 (0.39) | — | |
| SCHEMBL13736831 | 0.86 | CYP2C19 (0.39) | — | |
| SCHEMBL762293 | 0.83 | — | — | |
| SCHEMBL7406547 | 0.82 | KDM4E (0.38) | — | |
| SCHEMBL17049038 | 0.80 | MEN1 (0.34) | — | |
| SCHEMBL106415 | 0.79 | — | — | |
| SCHEMBL8641820 | 0.79 | FFAR3 (0.44) | — | |
| SCHEMBL18215019 | 0.78 | USP2 (0.43) | — | |
| SCHEMBL8950435 | 0.78 | LMNA (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115160116-B | Preparation method of cyclopropyl methyl ketone | 北京航天试验技术研究所 | 2024-01-26 | — | — | CN | claimed |
| US-12617762-B2 | Carboxy derivatives with antiinflamatory properties | SITRYX THERAPEUTICS LIMITED (GB) | 2026-05-05 | — | — | US | disclosed |
| EP-4081511-B3 | CARBOXY DERIVATIVES WITH ANTIINFLAMMATORY PROPERTIES | SITRYX THERAPEUTICS LTD (GB) | 2026-03-04 | — | — | EP | disclosed |
| EP-4442319-A2 | CARBOXY DERIVATIVES WITH ANTIINFLAMMATORY PROPERTIES | Sitryx Therapeutics Limited (GB) | 2024-10-09 | — | — | EP | disclosed |
| EP-4081511-B1 | CARBOXY DERIVATIVES WITH ANTIINFLAMMATORY PROPERTIES | SITRYX THERAPEUTICS LTD (GB) | 2024-07-31 | — | — | EP | disclosed |
| CN-115160116-B | Preparation method of cyclopropyl methyl ketone | 北京航天试验技术研究所 | 2024-01-26 | — | — | CN | disclosed |
| CN-115160116-B | Preparation method of cyclopropyl methyl ketone | 北京航天试验技术研究所 | 2024-01-26 | — | — | CN | disclosed |
| US-20230399287-A1 | NOVEL COMPOUNDS | SITRYX THERAPEUTICS LIMITED (GB) | 2023-12-14 | — | — | US | disclosed |
| US-20230399285-A1 | ILLUDIN ANALOGS, USES THEREOF, AND METHODS FOR SYNTHESIZING THE SAME | LANTERN PHARMA INC. (US) | 2023-12-14 | — | — | US | disclosed |
| US-20230399285-A1 | ILLUDIN ANALOGS, USES THEREOF, AND METHODS FOR SYNTHESIZING THE SAME | LANTERN PHARMA INC. (US) | 2023-12-14 | — | — | US | disclosed |
| US-5977133-A | Pyridone antibiotic with improved safety profile | ABBOTT LABORATORIES (US) | 1999-11-02 | — | — | US | disclosed |
| CN-1036193-C | Preparation of a sprio compound | DAIICHI SEIYAKU CO (JP) | 1997-10-22 | — | — | CN | disclosed |
| US-5508428-A | Spiro compound | DAIICHI PHAMACEUTICAL CO., LTD. (JP) | 1996-04-16 | — | — | US | disclosed |
| CN-1028102-C | Preparation of spiro compounds | DAIICHI SEIYAKU CO (JP) | 1995-04-05 | — | — | CN | disclosed |
| CN-1100095-A | Preparation of a sprio compound | DAIICHI SEIYAKU CO (JP) | 1995-03-15 | — | — | CN | disclosed |
| US-5286723-A | Spiro compound | DAIICHI SEIYAKU CO., LTD. | 1994-02-15 | — | — | US | disclosed |
| EP-0357047-B1 | Spiro compounds | DAIICHI SEIYAKU CO (JP) | 1993-11-03 | — | — | EP | disclosed |
| EP-0529688-A2 | Azaspiro n,m alkanes and diazaspiro n,m -alkanes | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1993-03-03 | — | — | EP | disclosed |
| CN-1040790-A | Preparation of spiro compounds | DAIICHI SEIYAKU CO (JP) | 1990-03-28 | — | — | CN | disclosed |
| EP-0357047-A1 | Spiro compounds | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1990-03-07 | — | — | EP | disclosed |