Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 15/20 | 0.71 |
| ▸ | BACE1 | P56817 | 15/20 | 0.71 |
| ▸ | BCHE | P06276 | 12/20 | 0.71 |
| ▸ | HTR5A | P47898 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7218189 | 0.88 | ACHE (0.85) | ACHEBACE1BCHEHTR5AMEN1 | |
| SCHEMBL14367985 | 0.84 | ACHE (1.00) | ACHEBACE1BCHEHTR5AMEN1 | |
| SCHEMBL7695906 | 0.84 | ACHE (0.92) | ACHEBACE1BCHEHTR5AMEN1 | |
| SCHEMBL7696728 | 0.81 | ACHE (0.71) | ACHEBACE1BCHEHTR5AMEN1 | |
| SCHEMBL7690757 | 0.81 | ACHE (0.71) | ACHEBACE1BCHEHTR5AMEN1 | |
| SCHEMBL1803081 | 0.80 | ACHE (1.00) | ACHEBACE1BCHEHTR5AMEN1 | |
| SCHEMBL8805748 | 0.80 | ACHE (0.74) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL20492752 | 0.80 | ACHE (0.74) | ACHEBACE1BCHEHTR5AMEN1 | |
| SCHEMBL7695218 | 0.80 | ACHE (0.69) | ACHEBACE1BCHEHTR5AMEN1 | |
| SCHEMBL20492760 | 0.79 | ACHE (1.00) | ACHEBACE1BCHEHTR5AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002083641-A2 | AMINO-AZA-CYCLOHEXANES FOR THE TREATMENT OF MALARIA | ACTELION PHARMACEUTICALS LTD. (CH) | 2002-10-24 | — | — | WO | disclosed |