Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 7/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.53 |
| ▸ | MMP2 | P08253 | 6/20 | 0.48 |
| ▸ | MMP9 | P14780 | 5/20 | 0.48 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7699204 | 0.96 | ITGB3 (0.51) | ITGB3ITGA2BMMP2MMP9ADAMTS4 | |
| SCHEMBL7420817 | 0.91 | ITGB3 (0.56) | ITGB3ITGA2BMMP2MMP9ADAMTS4 | |
| SCHEMBL7409585 | 0.91 | ITGB3 (0.61) | ITGB3ITGA2BMMP2MMP9ADAMTS4 | |
| SCHEMBL7417646 | 0.90 | MMP2 (0.56) | ITGB3ITGA2BMMP2MMP9ADAMTS4 | |
| SCHEMBL7410503 | 0.90 | ITGB3 (0.52) | ITGB3ITGA2BMMP2MMP9ADAMTS4 | |
| SCHEMBL7420563 | 0.90 | MMP2 (0.61) | ITGB3ITGA2BMMP2MMP9ADAMTS4 | |
| SCHEMBL7415221 | 0.90 | ITGB3 (0.53) | ITGB3ITGA2BMMP2MMP9ADAMTS4 | |
| SCHEMBL7412146 | 0.90 | MMP2 (0.56) | ITGB3ITGA2BMMP2MMP9ADAMTS4 | |
| SCHEMBL7409554 | 0.90 | MMP2 (0.61) | ITGB3ITGA2BMMP2MMP9ADAMTS4 | |
| SCHEMBL7411712 | 0.90 | TDP1 (0.59) | ITGB3ITGA2BMMP2MMP9ADAMTS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6344484-B1 | TREATMENT OF TUMOR GROWTH, METASTASIS, OSTEOPOROSIS, RESTENOSIS, INFLAMMATION, MACULAR DEGENERATION, DIABETIC RETINOPATHY, AND RHEUMATOID ARTHRITIS | 3-DIMENSIONAL PHARMACEUTICALS, INC. | 2002-02-05 | — | — | US | claimed |