Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 7/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7701095 | 0.92 | CA9 (0.35) | PARP1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL7694853 | 0.92 | PARP1 (0.34) | PARP1KMT2A | |
| SCHEMBL7701052 | 0.90 | PARP1 (0.33) | PARP1 | |
| SCHEMBL7700710 | 0.88 | KMT2A (0.31) | PARP1KMT2A | |
| SCHEMBL7701257 | 0.87 | KMT2A (0.31) | PARP1KMT2A | |
| SCHEMBL7696977 | 0.85 | KMT2A (0.30) | KMT2A | |
| SCHEMBL7702070 | 0.85 | KMT2A (0.30) | KMT2A | |
| SCHEMBL7700274 | 0.85 | TP53 (0.30) | KMT2A | |
| SCHEMBL7700530 | 0.85 | MTNR1A (0.32) | KMT2A | |
| SCHEMBL7695184 | 0.85 | KMT2A (0.32) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6346527-B1 | 1-BENZOXEPIN DERIVATIVES USED IN THE PREVENTION OF SODIUM AND HYDROGEN ION EXCHANGE; CARDIOVASCULAR, KIDNEY AND BRAIN DISORDER TREATMENT; ARTERIOSCLEROSIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-02-12 | — | — | US | disclosed |
| EP-1073650-A1 | GUANIDINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-02-07 | — | — | EP | disclosed |
| WO-1999055690-A1 | GUANIDINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-11-04 | — | — | WO | disclosed |