Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7701257 | 0.93 | KMT2A (0.31) | KMT2APARP1 | |
| SCHEMBL7700274 | 0.91 | TP53 (0.30) | KMT2A | |
| SCHEMBL7696977 | 0.91 | KMT2A (0.30) | KMT2A | |
| SCHEMBL7697135 | 0.88 | PARP1 (0.43) | KMT2APARP1 | |
| SCHEMBL7702076 | 0.87 | SLC9A1 (0.38) | — | |
| SCHEMBL7703807 | 0.87 | MEN1 (0.35) | KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL6135636 | 0.86 | SLC9A1 (0.37) | — | |
| Hydrochloric Acid SCHEMBL6134781 | 0.86 | SLC9A1 (0.37) | — | |
| SCHEMBL7694853 | 0.86 | PARP1 (0.34) | KMT2APARP1 | |
| SCHEMBL7701095 | 0.86 | CA9 (0.35) | KMT2ANPC1RAB9APARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6346527-B1 | 1-BENZOXEPIN DERIVATIVES USED IN THE PREVENTION OF SODIUM AND HYDROGEN ION EXCHANGE; CARDIOVASCULAR, KIDNEY AND BRAIN DISORDER TREATMENT; ARTERIOSCLEROSIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-02-12 | — | — | US | disclosed |