Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 5/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7698607 | 0.86 | KMT2A (0.58) | NPY5RKMT2AMEN1ALDH1A1CYP2C9 | |
| SCHEMBL7702562 | 0.85 | NPY5R (0.61) | NPY5RKMT2AMEN1ALDH1A1CYP2C9 | |
| SCHEMBL3012277 | 0.82 | GBA1 (0.69) | NPY5RKMT2AMEN1ALDH1A1CYP2C9 | |
| SCHEMBL7698612 | 0.77 | NPY5R (0.77) | NPY5RKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL7971363 | 0.76 | NPY5R (0.58) | NPY5RKMT2AMEN1ALDH1A1CYP2C9 | |
| SCHEMBL31743772 | 0.76 | KMT2A (0.60) | NPY5RKMT2AMEN1ALDH1A1CYP2C9 | |
| SCHEMBL14606676 | 0.75 | GBA1 (0.59) | NPY5RKMT2AMEN1ALDH1A1CYP2C9 | |
| SCHEMBL14606725 | 0.75 | GBA1 (0.59) | NPY5RKMT2AMEN1ALDH1A1CYP2C9 | |
| SCHEMBL7698041 | 0.75 | KMT2A (0.67) | NPY5RKMT2AMEN1ALDH1A1CYP2C9 | |
| SCHEMBL7971400 | 0.75 | NPY5R (0.72) | NPY5RKMT2AMEN1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002057220-A1 | HYDRAZIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2002-07-25 | — | — | WO | disclosed |