Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7697188 | 0.86 | NPY5R (0.67) | KMT2AMEN1POLBCYP3A4CYP2C19 | |
| SCHEMBL4390037 | 0.80 | KMT2A (0.60) | KMT2AMEN1POLBCYP3A4CYP2C19 | |
| SCHEMBL4390035 | 0.80 | KMT2A (0.60) | KMT2AMEN1POLBCYP3A4CYP2C19 | |
| SCHEMBL4007108 | 0.79 | GBA1 (0.56) | KMT2AMEN1POLBALDH1A1CYP2C9 | |
| SCHEMBL7698803 | 0.78 | KMT2A (0.62) | KMT2AMEN1POLBALDH1A1CYP2C9 | |
| SCHEMBL7698612 | 0.75 | NPY5R (0.77) | KMT2AMEN1POLBNPY5RALDH1A1 | |
| SCHEMBL7698693 | 0.75 | KMT2A (0.52) | KMT2AMEN1POLBCYP3A4CYP2C19 | |
| SCHEMBL13590685 | 0.74 | ACACB (0.70) | KMT2AMEN1POLBCYP3A4CYP2C19 | |
| SCHEMBL7971400 | 0.73 | NPY5R (0.72) | KMT2AMEN1POLBNPY5RALDH1A1 | |
| SCHEMBL7700849 | 0.73 | ALDH1A1 (0.72) | KMT2AMEN1POLBNPY5RALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002057220-A1 | HYDRAZIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2002-07-25 | — | — | WO | disclosed |