Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | GBA1 | P04062 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31743772 | 0.95 | KMT2A (0.60) | KMT2AHTTMAPK1GBA1ATM | |
| SCHEMBL3012277 | 0.92 | GBA1 (0.69) | KMT2AHTTMAPK1GBA1ATM | |
| SCHEMBL6624619 | 0.84 | SIGMAR1 (0.57) | KMT2AHTTMAPK1ATMSIGMAR1 | |
| SCHEMBL14606725 | 0.84 | GBA1 (0.59) | KMT2AHTTMAPK1GBA1ATM | |
| SCHEMBL14606676 | 0.84 | GBA1 (0.59) | KMT2AHTTMAPK1GBA1ATM | |
| SCHEMBL23048254 | 0.84 | GBA1 (0.55) | KMT2AHTTMAPK1GBA1ATM | |
| SCHEMBL16825749 | 0.84 | HTR2C (0.57) | KMT2AHTTMAPK1GBA1ATM | |
| SCHEMBL28113177 | 0.84 | KMT2A (0.67) | KMT2AHTTGBA1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7699722 | 0.84 | KMT2A (0.68) | KMT2AGBA1ATMALDH1A1SMN1; SMN2 | |
| SCHEMBL8396377 | 0.83 | GBA1 (0.83) | KMT2AGBA1ALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002057220-A1 | HYDRAZIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2002-07-25 | — | — | WO | disclosed |