Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.42 |
| ▸ | PADI3 | Q9ULW8 | 1/20 | 0.42 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.42 |
| ▸ | PADI2 | Q9Y2J8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | ECE1 | P42892 | 1/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7694342 | 0.81 | ECE1 (0.36) | PDE4APDE4BPDE4CPDE4DPADI1 | |
| Potassium SCHEMBL7262757 | 0.81 | ECE1 (0.36) | PDE4APDE4BPDE4CPDE4DPADI1 | |
| Potassium Ion SCHEMBL7262753 | 0.71 | ADORA2A (0.31) | ADORA2AADORA1 | |
| SCHEMBL6766149 | 0.69 | KDM4E (0.36) | KDM4EALOX15TSHRACMSDTDP1 | |
| SCHEMBL221380 | 0.65 | KDM4E (0.70) | PDE4APDE4BPDE4CPDE4DPADI1 | |
| SCHEMBL29956648 | 0.65 | KDM4E (0.70) | PDE4APDE4BPDE4CPDE4DPADI1 | |
| SCHEMBL28053317 | 0.64 | KDM4E (0.51) | KDM4EALOX15TSHRACMSDTDP1 | |
| SCHEMBL14610321 | 0.64 | KDM4E (0.48) | KDM4EALOX15TSHRACMSDTDP1 | |
| Hydrazine SCHEMBL28321699 | 0.64 | KDM4E (0.67) | PDE4APDE4BPDE4CPDE4DPADI1 | |
| SCHEMBL11907722 | 0.63 | MAP2K3 (0.51) | PDE4APDE4BPDE4CPDE4DPADI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002014465-A2 | MULTICYCLIC AROMATIC COMPOUNDS AND USES THEREOF | ROCHE DIAGNOSTICS CORPORATION (US) | 2002-02-21 | — | — | WO | disclosed |