SCHEMBL6766149

SCHEMBL6766149

O=C(O)c1ccc2c(n1)-c1nc3ncncc3cc1CC2

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.36
KMT2A Q03164 2/20 0.36
MEN1 O00255 1/20 0.36
LMNA P02545 1/20 0.36
ECE1 P42892 1/20 0.32
PIK3CG P48736 1/20 0.32
TDP1 Q9NUW8 2/20 0.31
GLA P06280 1/20 0.31
HTT P42858 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HIF1A Q16665 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
P4HA1 P13674 1/20 0.31
MIF P14174 1/20 0.31
P4HTM Q9NXG6 1/20 0.31
ALOX15 P16050 1/20 0.31
TSHR P16473 1/20 0.31
ACMSD Q8TDX5 1/20 0.31
ALDH1A1 P00352 1/20 0.30
KMO O15229 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5564401 0.75 KDM4E (0.56) KDM4EKMT2AMEN1LMNATDP1
SCHEMBL14610321 0.68 KDM4E (0.48) KDM4EKMT2AMEN1LMNAECE1
SCHEMBL353198 0.66 HCAR2 (0.35) KDM4EKMT2AMEN1PIK3CGTDP1
SCHEMBL7694342 0.66 ECE1 (0.36) KDM4EKMT2AMEN1ECE1TDP1
SCHEMBL28053317 0.65 KDM4E (0.51) KDM4ELMNATDP1HTTALOX15
SCHEMBL5566411 0.64 LCK (0.41) KDM4EKMT2AMEN1LMNATSHR
SCHEMBL6766148 0.63 ALDH1A1 (0.41) KDM4EKMT2AMEN1LMNAECE1
SCHEMBL6260367 0.62 ALOX15 (0.50) KDM4EKMT2AMEN1LMNAECE1
SCHEMBL29656527 0.62 MGAM (0.47) KDM4EKMT2AMEN1LMNAHIF1A
SCHEMBL1650336 0.62 MGAM (0.47) KDM4EKMT2AMEN1LMNAHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6720188-B2 MONITORING THE CONCENTRATION OF ARGININE IN SAMPLE; OBTAIN SAMPLE, INCUBATE WITH BINDING PARTICLE, DETERMINE ARGININE CONCENTRATION IN SAMPLE FAL DIAGNOSTICS 2004-04-13 US disclosed
EP-1299398-A1 METHODS AND KITS FOR THE DETECTION OF ARGININE COMPOUNDS Fal Diagnostics (US) 2003-04-09 EP disclosed
WO-2002004465-A1 METHODS AND KITS FOR THE DETECTION OF ARGININE COMPOUNDS FAL DIAGNOSTICS (US) 2002-01-17 WO disclosed