Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.73 |
| ▸ | BACE1 | P56817 | 14/20 | 0.73 |
| ▸ | BCHE | P06276 | 11/20 | 0.73 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | HTR5A | P47898 | 2/20 | 0.64 |
| ▸ | CCR3 | P51677 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7695910 | 0.86 | ACHE (0.72) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL7695906 | 0.86 | ACHE (0.92) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL7218189 | 0.86 | ACHE (0.85) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL20492760 | 0.84 | ACHE (1.00) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL14367985 | 0.84 | ACHE (1.00) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL1803081 | 0.80 | ACHE (1.00) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL4205093 | 0.79 | ACHE (1.00) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL16055288 | 0.79 | ACHE (0.85) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL7214418 | 0.79 | ACHE (1.00) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL7690757 | 0.78 | ACHE (0.71) | ACHEBACE1BCHEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002083641-A2 | AMINO-AZA-CYCLOHEXANES FOR THE TREATMENT OF MALARIA | ACTELION PHARMACEUTICALS LTD. (CH) | 2002-10-24 | — | — | WO | disclosed |