Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.46 |
| ▸ | ITGAV | P06756 | 3/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 16/20 | 0.45 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.42 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.42 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7698310 | 0.99 | ITGB3 (0.45) | ITGB3ITGAVITGA2BCASP1ITGB1 | |
| SCHEMBL7681991 | 0.87 | CASP1 (0.53) | CASP1 | |
| SCHEMBL7677209 | 0.86 | CASP1 (0.46) | ITGB3ITGAVCASP1 | |
| Hydrochloric Acid SCHEMBL7693610 | 0.85 | CASP1 (0.46) | ITGB3ITGAVCASP1 | |
| SCHEMBL7684370 | 0.83 | MAPK1 (0.46) | CASP1 | |
| SCHEMBL7701528 | 0.83 | ITGB3 (0.46) | ITGB3ITGAVITGA2BCASP1 | |
| SCHEMBL7700640 | 0.83 | CASP1 (0.46) | CASP1 | |
| SCHEMBL7677049 | 0.83 | CASP1 (0.56) | CASP1 | |
| SCHEMBL7684172 | 0.83 | CASP1 (0.51) | CASP1 | |
| Hydrochloric Acid SCHEMBL7696251 | 0.83 | ITGB3 (0.45) | ITGB3ITGAVITGA2BCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376484-B1 | FOR PREVENTION AND/OR TREATMENT OF VARIOUS KINDS OF INFLAMMATORY DISEASE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-04-23 | — | — | US | claimed |
| EP-0900791-A1 | TETRAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-03-10 | — | — | EP | claimed |
| US-6136834-A | TETRAZOLE PEPTIDES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0900791-A1 | TETRAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-03-10 | — | — | EP | disclosed |