Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.45 |
| ▸ | PCSK9 | Q8NBP7 | 5/20 | 0.41 |
| ▸ | MC5R | P33032 | 1/20 | 0.39 |
| ▸ | MC1R | Q01726 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30065739 | 0.81 | AHR (0.50) | AHRMC5RMC1RKDM4ECYP1A2 | |
| SCHEMBL951816 | 0.81 | AHR (0.50) | AHRMC5RMC1RKDM4ECYP1A2 | |
| 2-Methylindole SCHEMBL2683930 | 0.76 | AHR (0.63) | AHRKDM4EGAARXFP1CYP1A2 | |
| 2-Methylindole SCHEMBL11381962 | 0.76 | KDM4E (0.49) | KDM4EGAARXFP1CYP1A2DAO | |
| 2-Methylindole SCHEMBL28273394 | 0.74 | BRD4 (0.53) | KDM4EGAARXFP1CYP1A2DAO | |
| 2-Methylindole SCHEMBL29377448 | 0.73 | BRD4 (0.57) | KDM4EGAARXFP1CYP1A2DAO | |
| 2-Methylindole SCHEMBL12420 | 0.73 | BRD4 (0.57) | KDM4EGAARXFP1CYP1A2DAO | |
| 2-Methylindole SCHEMBL28979125 | 0.73 | AKR1C3 (0.50) | KDM4EGAARXFP1CYP1A2DAO | |
| 2-Methylindole SCHEMBL27946379 | 0.72 | ATM (0.67) | AHRPCSK9MC5RMC1RKDM4E | |
| 2-Methylindole SCHEMBL31025706 | 0.72 | BRD4 (0.55) | KDM4EGAARXFP1CYP1A2DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002079153-A1 | METHOD FOR PRODUCING TRYPTAMINE DERIVATIVES | BIOCATALYTICS, INC. (US) | 2002-10-10 | — | — | WO | disclosed |