Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 2/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | GLS | O94925 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30065739 | 1.00 | AHR (0.50) | AHRDAOPIK3CDCYP3A4MEN1 | |
| SCHEMBL6536568 | 0.84 | AHR (0.47) | AHRDAOPIK3CDCYP3A4MEN1 | |
| SCHEMBL7410348 | 0.83 | HTR1A (0.40) | AHRDAOPIK3CDCYP3A4MEN1 | |
| Tert-Butyl Formate SCHEMBL27892365 | 0.82 | DAO (0.39) | AHRDAOTDP1GLSBCHE | |
| Ethoxycarbonyl Group SCHEMBL28293163 | 0.82 | PKM (0.41) | AHRDAOCYP3A4MEN1KMT2A | |
| SCHEMBL1880679 | 0.81 | AHR (0.44) | AHRDAOPIK3CDMAPK1GLS | |
| 2-Methylindole SCHEMBL7697406 | 0.81 | AHR (0.45) | AHRDAOMEN1KMT2AMAPT | |
| SCHEMBL11032690 | 0.80 | GLS (0.45) | AHRDAOPIK3CDMAPK1GLS | |
| SCHEMBL2633083 | 0.79 | DAO (0.50) | AHRDAOPIK3CDCYP3A4MEN1 | |
| SCHEMBL8051283 | 0.79 | AHR (0.50) | AHRDAOPIK3CDCYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 271 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113173925-B | Benzoxoepinoindole derivative and preparation method thereof | 浙江大学 | 2022-11-11 | — | — | CN | claimed |
| CN-112402385-B | 4-hydroxymethyl-1H-indole compound pharmaceutical preparation and preparation method thereof | 北京华氏开元医药科技有限公司 | 2022-04-01 | — | — | CN | claimed |
| CN-113173925-A | Benzoxoepinoindole derivative and preparation method thereof | 浙江大学 | 2021-07-27 | — | — | CN | claimed |
| CN-112194652-B | 4-hydroxymethyl-1H-indole compound, preparation method and application | 北京华氏开元医药科技有限公司 | 2021-03-05 | — | — | CN | claimed |
| CN-112402385-A | 4-hydroxymethyl-1H-indole compound pharmaceutical preparation and preparation method thereof | 北京华氏开元医药科技有限公司 | 2021-02-26 | — | — | CN | claimed |
| CN-112194652-A | 4-hydroxymethyl-1H-indole compound, preparation method and application | 北京华氏开元医药科技有限公司 | 2021-01-08 | — | — | CN | claimed |
| EP-1067950-B1 | NEO-TRYPTOPHAN | MAYO FOUNDATION (US) | 2008-05-14 | — | — | EP | claimed |
| US-6765099-B2 | NOVEL AMINO ACID, NEO-TRYPTOPHAN, AS WELL AS POLYPEPTIDES CONTAINING THIS NOVEL AMINO ACID SUCH AS NEUROTENSIN ANALOGS. IN ADDITION, THE INVENTION PROVIDES NEO- TRYPTOPHAN DERIVATIVES, SEROTONIN-LIKE NEO-TRYPTOPHAN DERIVATIVES AND | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH | 2004-07-20 | — | — | US | claimed |
| US-20030166505-A1 | Neo-tryptophan | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH, A MINNESOTA CORPORATION | 2003-09-04 | — | — | US | claimed |
| WO-2002080906-A1 | PREVENTION AND TREATMENT OF ENDOMETRIOSIS WITH ARYL HYDROCARBON RECEPTOR BINDING LIGANDS | CEDARS-SINAI MEDICAL CENTER (US) | 2002-10-17 | — | — | WO | claimed |
| US-20020147155-A1 | Prevention and treatment of endometriosis with aryl hydrocarbon receptor binding ligands | CEDARS-SINAI MEDICAL CENTER | 2002-10-10 | — | — | US | claimed |
| US-20010027174-A1 | Neo-tryptophan | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH MINNESOTA CORPORATION | 2001-10-04 | — | — | US | claimed |
| EP-1067950-A4 | NEO-TRYPTOPHAN | MAYO FOUNDATION FOR MEDICAL (US) | 2001-09-05 | — | — | EP | claimed |
| US-6214790-B1 | POLYPEPTIDES OF NEOTRYPTOPHAN AND SYNTHESIS | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH | 2001-04-10 | — | — | US | claimed |
| EP-1067950-A1 | NEO-TRYPTOPHAN | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2001-01-17 | — | — | EP | claimed |
| WO-1999052539-A1 | NEO-TRYPTOPHAN | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 1999-10-21 | — | — | WO | claimed |
| US-20250115572-A1 | SPIROCYCLIC PIPERIDINYL DERIVATIVES AS COMPLEMENT FACTOR B INHIBITORS AND USES THEREOF | NOVARTIS PHARMA AG (CH) | 2025-04-10 | — | — | US | disclosed |
| EP-4469157-A1 | SPIROCYCLIC PIPERIDINYL DERIVATIVES AS COMPLEMENT FACTOR B INHIBITORS AND USES THEREOF | Novartis AG (CH) | 2024-12-04 | — | — | EP | disclosed |
| EP-0099766-A1 | 1-3-Dihydro 4-(1-hydroxy-2-amino-ethyl)-2H-indol-2-one derivatives, their salts, process for their preparation, their use as medicines and compositions containing them | ROUSSEL-UCLAF (FR) | 1984-02-01 | — | — | EP | disclosed |
| EP-0076713-A1 | Aminomethyl-1H-indole-4-methanol derivatives and their salts, process and intermediates for their preparation, their use as medicines and compositions containing them | ROUSSEL-UCLAF (FR) | 1983-04-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030166505-A1 | Neo-tryptophan | NTSR1, NTSR2, TPH1 | AHR 743/4885DAO 189/4885PIK3CD 3622/4885 |
| US-20250115572-A1 | SPIROCYCLIC PIPERIDINYL DERIVATIVES AS COMPLEMENT FACTOR B INHIBITORS AND USES THEREOF | CFB, C1QBP, CFH | AHR 3209/4885DAO 3767/4885PIK3CD 705/4885 |
| US-20010027174-A1 | Neo-tryptophan | NTSR1, NTSR2, TPH1 | AHR 743/4885DAO 189/4885PIK3CD 3622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.