SCHEMBL7697488

SCHEMBL7697488

O=C(O)c1nccc(F)n1

nearest known ligand 0.53

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KMO O15229 18/20 0.53
KDM4E B2RXH2 1/20 0.42
ASPH Q12797 1/20 0.42
KDM8 Q8N371 1/20 0.42
NAPRT Q6XQN6 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31413728 1.00 KMO (0.53) KMOKDM4EASPHKDM8NAPRT
SCHEMBL24087665 0.81 KMO (0.37) KMOKDM4EASPHKDM8NAPRT
SCHEMBL7697331 0.80 KMO (0.42) KMO
SCHEMBL351032 0.76 KDM4E (0.40) KDM4E
SCHEMBL31126262 0.76 KDM4E (0.55) KMOKDM4EASPHKDM8NAPRT
SCHEMBL163539 0.76 KMO (0.50) KMO
SCHEMBL163540 0.76 KMO (0.50) KMOKDM4EASPHKDM8
SCHEMBL87765 0.76 KDM4E (0.55) KMOKDM4EASPHKDM8NAPRT
Fluoride SCHEMBL21332111 0.74 KDM4E (0.53) KMOKDM4EASPHKDM8NAPRT
SCHEMBL20929040 0.74 KMO (0.49) KMONAPRT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6337368-B1 WATER INSOLUBLE CARRIERS WITH P-NITROBENZOIC ACID, AROMATIC AMINES, AMIDES, SULFONAMIDES AND HYDRAZIDES KANEKA CORPORATION (JP) 2002-01-08 US disclosed
EP-1008383-A1 LIPOPROTEIN ADSORBENT AND LIPOPROTEIN ADSORBER MADE WITH THE USE OF THE SAME KANEKA CORPORATION (JP) 2000-06-14 EP disclosed