SCHEMBL24087665

SCHEMBL24087665

O=C(Cl)c1nccc(F)n1

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ KMO O15229 16/20 0.37
▸ KDM4E B2RXH2 1/20 0.33
▸ ASPH Q12797 1/20 0.33
▸ KDM8 Q8N371 1/20 0.33
▸ ALDH1A1 P00352 1/20 0.33
▸ ALOX15 P16050 1/20 0.33
▸ NAPRT Q6XQN6 1/20 0.31
▸ GRM5 P41594 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7697488 0.81 KMO (0.53) KMOKDM4EASPHKDM8NAPRT
SCHEMBL31413728 0.81 KMO (0.53) KMOKDM4EASPHKDM8NAPRT
SCHEMBL30368390 0.77 KMO (0.37) KMOKDM4EASPHKDM8ALDH1A1
SCHEMBL21173935 0.77 KMO (0.37) KMOKDM4EASPHKDM8ALDH1A1
SCHEMBL2773643 0.77 KMO (0.41) KMOALDH1A1NAPRT
SCHEMBL27956903 0.75 KMO (0.36) KMOKDM4EALDH1A1
SCHEMBL351032 0.75 KDM4E (0.40) KDM4EALDH1A1ALOX15
SCHEMBL31537115 0.75 TAS2R14 (0.42) KMO
SCHEMBL27986399 0.69 KMO (0.58) KMO
SCHEMBL2370675 0.69 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11444253-B2 Thermally activated delayed fluorescent material and preparation method thereof WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2022-09-13 — — US disclosed
US-20210384447-A1 THERMALLY ACTIVATED DELAYED FLUORESCENT MATERIAL AND PREPARATION METHOD THEREOF WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2021-12-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210384447-A1 THERMALLY ACTIVATED DELAYED FLUORESCENT MATERIAL AND PREPARATION METHOD THEREOF ALAD, CD69, ETFA KMO 3979/4885KDM4E 4793/4885ASPH 1455/4885
US-11444253-B2 Thermally activated delayed fluorescent material and preparation method thereof ALAD, CD69, ETFA KMO 3979/4885KDM4E 4793/4885ASPH 1455/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback