Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7695831 | 0.90 | DYRK1A (0.46) | KMT2AMEN1LRRK2KDM4EMAPT | |
| SCHEMBL7695942 | 0.87 | MEN1 (0.50) | KMT2AMEN1LRRK2KDM4EMAPT | |
| SCHEMBL7701567 | 0.84 | LRRK2 (0.50) | KMT2AMEN1LRRK2KDM4ETSHR | |
| SCHEMBL8991072 | 0.82 | LRRK2 (0.51) | KMT2AMEN1LRRK2KDM4EPIK3CD | |
| SCHEMBL8991109 | 0.81 | KDM4E (0.59) | KMT2AMEN1LRRK2KDM4ETSHR | |
| SCHEMBL7700961 | 0.80 | PAX8 (0.44) | KMT2AMEN1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL7705445 | 0.77 | DYRK1A (0.49) | KMT2AMEN1LRRK2KDM4EPIK3CD | |
| SCHEMBL7700997 | 0.77 | LRRK2 (0.55) | KMT2AMEN1LRRK2KDM4EPIK3CD | |
| SCHEMBL7696350 | 0.76 | LRRK2 (0.53) | KMT2AMEN1LRRK2KDM4ETSHR | |
| SCHEMBL7695719 | 0.76 | LRRK2 (0.53) | KMT2ALRRK2KDM4EPIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342501-B1 | VIRICIDES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-01-29 | — | — | US | disclosed |