Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 8/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7696391 | 0.91 | MAPT (0.54) | KDM4EKMT2AHSD17B10DGAT1MAPT | |
| SCHEMBL7700066 | 0.91 | NPC1 (0.58) | KDM4EKMT2AHSD17B10DGAT1MAPT | |
| SCHEMBL7699504 | 0.91 | MAPT (0.55) | KDM4EKMT2ADGAT1MAPTL3MBTL1 | |
| SCHEMBL7697612 | 0.89 | L3MBTL1 (0.60) | KMT2ADGAT1MAPTL3MBTL1TP53 | |
| SCHEMBL7699501 | 0.88 | MAPT (0.55) | KMT2AHSD17B10DGAT1MAPTL3MBTL1 | |
| SCHEMBL7703296 | 0.88 | DGAT1 (0.51) | KDM4EHSD17B10DGAT1MAPTL3MBTL1 | |
| SCHEMBL7695770 | 0.86 | MAPT (0.58) | KDM4EHSD17B10DGAT1MAPTL3MBTL1 | |
| SCHEMBL7695332 | 0.85 | NPC1 (0.56) | KDM4EKMT2AHSD17B10DGAT1MAPT | |
| SCHEMBL7697962 | 0.85 | L3MBTL1 (0.56) | KDM4EKMT2ADGAT1MAPTL3MBTL1 | |
| SCHEMBL7699160 | 0.84 | SMN1; SMN2 (0.57) | KDM4EKMT2AHSD17B10DGAT1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |