Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18324783 | 0.85 | KDM4E (0.47) | GAAALDH1A1KDM4EBRD4POLB | |
| SCHEMBL18324980 | 0.82 | KDM4E (0.56) | GAAALDH1A1KDM4EBRD4POLB | |
| SCHEMBL3239199 | 0.76 | KDM4E (0.67) | ALDH1A1KDM4EBRD4POLBCREBBP | |
| SCHEMBL13677410 | 0.74 | KDM4E (0.54) | KMT2AALDH1A1KDM4EBRD4POLB | |
| SCHEMBL18324710 | 0.73 | KDM4E (0.57) | GAAKMT2AALDH1A1KDM4EBRD4 | |
| SCHEMBL3231094 | 0.72 | ALDH1A1 (0.52) | GAAKMT2AALDH1A1KDM4EBRD4 | |
| SCHEMBL20016371 | 0.72 | KDM4E (0.48) | GAAALDH1A1KDM4EBRD4POLB | |
| SCHEMBL4860623 | 0.72 | KDM4E (0.53) | GAAKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL18324702 | 0.71 | ALDH1A1 (0.53) | ALDH1A1KDM4EBRD4POLBCREBBP | |
| SCHEMBL18325013 | 0.71 | KDM4E (0.53) | KMT2AMEN1ALDH1A1KDM4EBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002079190-A1 | 3-SUBSTITUTED INDOLES AS CHEMOKINE ANTAGONISTS | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-10-10 | — | — | WO | disclosed |