Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 4/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | CTSA | P10619 | 6/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.32 |
| ▸ | ITGAV | P06756 | 1/20 | 0.32 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7684373 | 0.88 | CASP1 (0.39) | CASP1CNR2ITGA4MAPTTHRB | |
| SCHEMBL7680032 | 0.86 | CASP1 (0.48) | CASP1CNR2CASP3 | |
| SCHEMBL7683927 | 0.86 | CASP1 (0.41) | CASP1CNR2MAPTTHRBALDH1A1 | |
| SCHEMBL7680872 | 0.85 | CASP1 (0.49) | CASP1CNR2CASP3 | |
| SCHEMBL7682110 | 0.85 | CASP1 (0.42) | CASP1CNR2MAPTTHRBCASP3 | |
| SCHEMBL7684191 | 0.84 | ALDH1A1 (0.41) | CASP1CNR2CTSAMAPTALDH1A1 | |
| SCHEMBL7680363 | 0.83 | CASP1 (0.47) | CASP1CNR2SMN1; SMN2CASP3 | |
| SCHEMBL8177183 | 0.83 | CASP1 (0.40) | CASP1CNR2MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL7683599 | 0.83 | CASP1 (0.50) | CASP1CNR2CASP3 | |
| SCHEMBL7683810 | 0.83 | CASP1 (0.46) | CASP1CNR2CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376484-B1 | FOR PREVENTION AND/OR TREATMENT OF VARIOUS KINDS OF INFLAMMATORY DISEASE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-04-23 | — | — | US | claimed |