Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7697991 | 1.00 | ALOX5 (0.50) | ALOX5TP53MEN1KMT2ATDP1 | |
| SCHEMBL7697986 | 0.93 | ALOX5 (0.51) | ALOX5TP53MEN1KMT2ATDP1 | |
| SCHEMBL15751973 | 0.91 | ALOX5 (0.54) | ALOX5TDP1SMN1; SMN2CYP3A4PTPN2 | |
| SCHEMBL7232896 | 0.84 | ALOX5 (0.46) | ALOX5TP53MEN1KMT2ATDP1 | |
| SCHEMBL232779 | 0.84 | TP53 (0.64) | ALOX5TP53MEN1KMT2ATDP1 | |
| SCHEMBL6415003 | 0.84 | POLB (0.42) | TP53TDP1SMN1; SMN2HTTKDM4E | |
| SCHEMBL28557809 | 0.82 | TP53 (0.55) | ALOX5TP53MEN1KMT2ATDP1 | |
| SCHEMBL9133420 | 0.82 | TP53 (0.62) | ALOX5TP53MEN1KMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL3088495 | 0.82 | TP53 (0.62) | ALOX5TP53MEN1KMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL2299193 | 0.82 | TP53 (0.62) | ALOX5TP53MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002002520-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-01-10 | — | — | WO | disclosed |