Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 7/20 | 0.56 |
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | MPO | P05164 | 1/20 | 0.55 |
| ▸ | STAT3 | P40763 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7701071 | 0.89 | TSHR (0.63) | MAPTTP53THRBRAB9ANPC1 | |
| SCHEMBL7701897 | 0.88 | KDM4E (0.55) | MAPTRAB9ANPC1KMT2AKDM4E | |
| SCHEMBL3127884 | 0.88 | IKBKB (0.56) | MAPTRAB9ANPC1KMT2AMEN1 | |
| SCHEMBL7698000 | 0.86 | KDM4E (0.65) | MAPTTP53THRBRAB9ANPC1 | |
| SCHEMBL7695319 | 0.86 | MAPT (0.57) | MAPTTP53RAB9ANPC1KMT2A | |
| SCHEMBL7701088 | 0.85 | MAPT (0.53) | MAPTTP53STAT3KDM4EGAA | |
| SCHEMBL7697604 | 0.84 | KDM4E (0.55) | MAPTTP53RAB9ANPC1KMT2A | |
| SCHEMBL7696428 | 0.83 | STAT3 (0.55) | MAPTTP53RAB9ANPC1KMT2A | |
| SCHEMBL7697462 | 0.83 | MAPT (0.59) | MAPTTP53THRBRAB9ANPC1 | |
| SCHEMBL7696456 | 0.81 | MAPT (0.51) | MAPTTP53THRBRAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |