Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | NAMPT | P43490 | 3/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | ALPI | P09923 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | XIAP | P98170 | 1/20 | 0.49 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.49 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.48 |
| ▸ | CTSC | P53634 | 1/20 | 0.47 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7692756 | 0.99 | NAMPT (0.53) | GAANAMPTHDAC8HPGDTSHR | |
| SCHEMBL7694793 | 0.88 | SLC7A5 (0.49) | GAAHDAC8SLC7A5 | |
| SCHEMBL7696633 | 0.87 | DPP7 (0.60) | DPP7 | |
| SCHEMBL4311269 | 0.86 | MMP8 (0.56) | GAANAMPTHDAC8HPGDALPI | |
| SCHEMBL7404833 | 0.86 | MMP8 (0.56) | GAANAMPTHDAC8HPGDALPI | |
| SCHEMBL7412711 | 0.84 | NAMPT (0.48) | NAMPTHDAC8ALPIPKMPTGS1 | |
| SCHEMBL7692760 | 0.83 | DPP7 (0.48) | GAAHPGDDPP7KDM4E | |
| SCHEMBL1039399 | 0.81 | HDAC8 (0.68) | GAAHDAC8HPGDTSHRALPI | |
| SCHEMBL8077871 | 0.81 | HDAC8 (0.68) | GAAHDAC8HPGDTSHRALPI | |
| SCHEMBL17844273 | 0.80 | ALPI (0.68) | NAMPTHDAC8ALPIPKMPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028829-A2 | PEPTIDE DEFORMYLASE INHIBITORS | QUESTCOR PHARMACEUTICALS, INC. (US) | 2002-04-11 | — | — | WO | claimed |