SCHEMBL7696633

SCHEMBL7696633

N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)NC(=O)N1CCCC1

nearest known ligand 0.60

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
DPP7 Q9UHL4 1/20 0.60
LNPEP Q9UIQ6 3/20 0.53
LTA4H P09960 5/20 0.50
HRH3 Q9Y5N1 4/20 0.50
NPC1 O15118 1/20 0.50
CASP3 P42574 1/20 0.50
RAB9A P51151 1/20 0.50
SENP8 Q96LD8 1/20 0.50
SENP7 Q9BQF6 1/20 0.50
SENP6 Q9GZR1 1/20 0.50
FAAH O00519 1/20 0.50
TP53 P04637 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
LAP3 P28838 1/20 0.49
HTT P42858 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7692756 0.88 NAMPT (0.53) DPP7
SCHEMBL7698022 0.87 GAA (0.52) DPP7
SCHEMBL7366398 0.84 DPP7 (0.71) DPP7LTA4HHRH3NPC1CASP3
SCHEMBL7373437 0.83 DPP7 (0.56) DPP7LNPEPLTA4HHRH3NPC1
SCHEMBL7367648 0.83 DPP7 (0.56) DPP7LNPEPLTA4HHRH3NPC1
SCHEMBL7694793 0.81 SLC7A5 (0.49) LNPEPNPC1RAB9A
SCHEMBL7371156 0.81 HTT (0.57) DPP7LNPEPLTA4HHRH3NPC1
SCHEMBL7698097 0.80 LNPEP (0.60) LNPEPLTA4HNPC1RAB9ASMN1; SMN2
SCHEMBL7365328 0.80 NPC1 (0.56) DPP7LTA4HHRH3NPC1RAB9A
SCHEMBL7341842 0.80 NPC1 (0.56) DPP7LTA4HHRH3NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002028829-A2 PEPTIDE DEFORMYLASE INHIBITORS QUESTCOR PHARMACEUTICALS, INC. (US) 2002-04-11 WO claimed