Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.41 |
| ▸ | PTGES | O14684 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 7/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LDLR | P01130 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7693513 | 0.88 | DGAT1 (0.48) | EPHX2PTGESCNR1CNR2ALDH1A1 | |
| SCHEMBL7702160 | 0.88 | EPHX2 (0.44) | EPHX2PTGESCNR1CNR2CETP | |
| SCHEMBL7700939 | 0.87 | HPGD (0.44) | EPHX2PTGESCNR1CNR2DGAT1 | |
| SCHEMBL7701069 | 0.87 | POLB (0.48) | EPHX2PTGESCNR1CNR2HTT | |
| SCHEMBL7699624 | 0.86 | DGAT1 (0.47) | EPHX2PTGESCNR1CNR2ALDH1A1 | |
| SCHEMBL7699158 | 0.86 | EPHX2 (0.45) | EPHX2PTGESCNR1CNR2DGAT1 | |
| SCHEMBL7700054 | 0.86 | NPC1 (0.50) | EPHX2PTGESCNR1CNR2ALDH1A1 | |
| SCHEMBL7696432 | 0.85 | CNR1 (0.43) | EPHX2PTGESCNR1CNR2ALDH1A1 | |
| SCHEMBL7701312 | 0.85 | CDC25A (0.46) | EPHX2PTGESCNR1CNR2ALDH1A1 | |
| SCHEMBL7696225 | 0.85 | EPHX2 (0.45) | EPHX2PTGESCNR1CNR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |