Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 8/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.43 |
| ▸ | PTGES | O14684 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7699158 | 0.96 | EPHX2 (0.45) | EPHX2CYP2C9PTGESCNR1CNR2 | |
| SCHEMBL7698147 | 0.87 | NCOA1 (0.42) | EPHX2PTGESCNR1CNR2DGAT1 | |
| SCHEMBL7700202 | 0.85 | EPHX2 (0.52) | HSD17B10EPHX2PTGESCNR1CNR2 | |
| SCHEMBL7693795 | 0.85 | KDM4E (0.51) | POLBSMN1; SMN2HSD17B10EPHX2PTGES | |
| SCHEMBL7700054 | 0.84 | NPC1 (0.50) | HPGDEPHX2PTGESCNR1CNR2 | |
| SCHEMBL7693811 | 0.84 | NPC1 (0.50) | HPGDPOLBSMN1; SMN2HSD17B10EPHX2 | |
| SCHEMBL7700947 | 0.84 | KDM4E (0.47) | HSD17B10EPHX2PTGESCNR1CNR2 | |
| SCHEMBL7698708 | 0.83 | CNR1 (0.49) | EPHX2CYP2C9PTGESCNR1CNR2 | |
| SCHEMBL7696225 | 0.83 | EPHX2 (0.45) | HPGDPOLBHSD17B10EPHX2CYP2C9 | |
| SCHEMBL7695821 | 0.82 | ECE1 (0.49) | HPGDSMN1; SMN2EPHX2CYP2C9PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |