Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.46 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD1 | P21728 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | PRCP | P42785 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL191727 | 0.79 | HTT (0.60) | HTTTAS1R3TAS1R1TAS1R2SMN1; SMN2 | |
| SCHEMBL3421659 | 0.79 | HTT (0.60) | HTTTAS1R3TAS1R1TAS1R2SMN1; SMN2 | |
| SCHEMBL191726 | 0.79 | HTT (0.60) | HTTTAS1R3TAS1R1TAS1R2SMN1; SMN2 | |
| SCHEMBL9011724 | 0.76 | HTT (0.75) | TSHRHTTTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL4751069 | 0.76 | HTR2C (0.56) | HTR2AHTR2CHTR2BTAAR1TSHR | |
| SCHEMBL23091569 | 0.75 | TSHR (0.58) | TSHRNPSR1HTTSMN1; SMN2MEN1 | |
| SCHEMBL8319836 | 0.75 | TSHR (0.58) | TSHRNPSR1HTTSMN1; SMN2MEN1 | |
| Malonic Acid SCHEMBL174816 | 0.74 | HTR2C (0.74) | HTR2AHTR2CHTR2BTAAR1TSHR | |
| SCHEMBL25037806 | 0.73 | SETD2 (0.49) | TAS1R3TAS1R1TAS1R2DRD2 | |
| SCHEMBL21739663 | 0.72 | TAS1R3 (0.37) | HTR2AHTR2CHTR2BTAAR1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002057258-A1 | CYCLO`D!AZEPANE DERIVATIVES WHICH ARE USED AS FARNESYLTRANSFERASE INHIBITORS AND METHOD FOR THE PREPARATION THEREOF | LES LABORATOIRES SERVIER (FR) | 2002-07-25 | — | — | WO | disclosed |