Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.44 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.43 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7699812 | 0.93 | MEN1 (0.56) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL7695519 | 0.90 | MAPT (0.61) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL7697100 | 0.90 | MAPT (0.47) | MEN1KMT2AMAPTRXFP1LMNA | |
| SCHEMBL7699503 | 0.85 | ALDH1A1 (0.56) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL7703333 | 0.83 | KDM4E (0.64) | NPC1RAB9AMAPTKDM4EGAA | |
| SCHEMBL7699977 | 0.82 | MAPT (0.49) | MEN1KMT2AMAPTRXFP1LMNA | |
| SCHEMBL7693822 | 0.81 | NR1H4 (0.48) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL7695082 | 0.80 | MAPT (0.50) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL7703211 | 0.80 | KDM4E (0.49) | NPC1RAB9AMAPTKDM4EGAA | |
| SCHEMBL7695211 | 0.79 | KDM4E (0.53) | NPC1RAB9AMAPTKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |