Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.44 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.44 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.44 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7699977 | 0.94 | MAPT (0.49) | MAPTRXFP1SIRT2SIRT1SIRT3 | |
| SCHEMBL7698294 | 0.90 | MEN1 (0.52) | MAPTRXFP1SIRT2SIRT1SIRT3 | |
| SCHEMBL7695493 | 0.87 | NR1H4 (0.44) | MAPTSIRT2SIRT1SIRT3PDK1 | |
| SCHEMBL7698238 | 0.85 | ALDH1A1 (0.55) | MAPTRXFP1MEN1KMT2AALDH1A1 | |
| SCHEMBL7699812 | 0.82 | MEN1 (0.56) | MAPTMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL7699232 | 0.80 | ALDH1A1 (0.47) | MAPTRXFP1SIRT1MEN1KMT2A | |
| SCHEMBL7695519 | 0.79 | MAPT (0.61) | MAPTRXFP1MEN1KMT2ATP53 | |
| SCHEMBL7695765 | 0.79 | ALDH1A1 (0.50) | MAPTRXFP1MEN1KMT2ATP53 | |
| SCHEMBL7701056 | 0.78 | MAPT (0.47) | MAPTRXFP1SIRT1MEN1KMT2A | |
| SCHEMBL7702798 | 0.77 | MAPT (0.50) | MAPTRXFP1TP53ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |