Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7706981 | 1.00 | SLC6A9 (0.59) | SLC6A9ALDH1A1MAPTRAB9AKDM4E | |
| Hydrochloric Acid SCHEMBL7708945 | 0.88 | SLC6A9 (0.73) | SLC6A9ALDH1A1MAPTKDM4EMTNR1A | |
| Hydrochloric Acid SCHEMBL7698457 | 0.86 | SLC6A9 (0.77) | SLC6A9MTNR1AMTNR1B | |
| SCHEMBL7700190 | 0.80 | SLC6A9 (0.65) | SLC6A9MAPTMAPK1 | |
| SCHEMBL7700569 | 0.78 | SLC6A9 (0.81) | SLC6A9MTNR1AMTNR1BMEN1KMT2A | |
| SCHEMBL7409984 | 0.78 | MTNR1A (0.52) | SLC6A9MAPTRAB9AMTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL7706317 | 0.77 | MTNR1A (0.51) | SLC6A9MAPTRAB9AMTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL7706314 | 0.77 | MTNR1A (0.51) | SLC6A9MAPTRAB9AMTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL7706319 | 0.77 | MTNR1A (0.51) | SLC6A9MAPTRAB9AMTNR1AMTNR1B | |
| SCHEMBL7700589 | 0.77 | SLC6A9 (0.62) | SLC6A9ALDH1A1MAPTKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100769-B1 | AMINOMETHYLCARBOXYLIC ACID DERIVATIVES | AKZO NOBEL NV (NL) | 2002-12-04 | — | — | EP | disclosed |
| US-6410592-B1 | THERAPY FOR CENTRAL NERVOUS SYSTEM DISORDERS, PSYCHOLOGICAL DISORDERS | AKZO NOBEL N.V. (NL) | 2002-06-25 | — | — | US | disclosed |