Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 12/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 12/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 10/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 10/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17507211 | 1.00 | CHRNB2 (0.36) | CHRNB2CHRNA4CHRNB4CHRNA3NPY5R | |
| SCHEMBL17507209 | 1.00 | CHRNB2 (0.36) | CHRNB2CHRNA4CHRNB4CHRNA3NPY5R | |
| SCHEMBL16115008 | 1.00 | CHRNB2 (0.36) | CHRNB2CHRNA4CHRNB4CHRNA3NPY5R | |
| SCHEMBL16139903 | 0.89 | CHRNA3 (0.34) | CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL17512217 | 0.89 | CHRNA3 (0.34) | CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL17512216 | 0.89 | CHRNA3 (0.34) | CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL16116218 | 0.89 | CHRNA3 (0.34) | CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL16115489 | 0.87 | BACE1 (0.36) | — | |
| SCHEMBL17512212 | 0.87 | BACE1 (0.36) | — | |
| SCHEMBL17512213 | 0.87 | BACE1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002057262-A2 | BICYCLIC AMINES AS INSECTICIDES | SYNGENTA LIMITED (GB) | 2002-07-25 | — | — | WO | disclosed |