Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.77 |
| ▸ | HTR6 | P50406 | 1/20 | 0.59 |
| ▸ | PPARD | Q03181 | 2/20 | 0.58 |
| ▸ | PPARG | P37231 | 1/20 | 0.58 |
| ▸ | PPARA | Q07869 | 1/20 | 0.58 |
| ▸ | YES1 | P07947 | 1/20 | 0.56 |
| ▸ | KDR | P35968 | 1/20 | 0.56 |
| ▸ | JAK3 | P52333 | 1/20 | 0.56 |
| ▸ | CDC25A | P30304 | 1/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | NPY1R | P25929 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8178903 | 0.93 | ALDH1A1 (0.67) | LMNAALDH1A1HTR6PPARDPPARG | |
| SCHEMBL2051630 | 0.91 | ALDH1A1 (0.80) | LMNAALDH1A1HTR6CDC25ACYP19A1 | |
| SCHEMBL28785168 | 0.91 | LMNA (0.65) | LMNAALDH1A1HTR6PPARDPPARG | |
| SCHEMBL8174654 | 0.91 | LMNA (0.68) | LMNAALDH1A1HTR6PPARDPPARG | |
| SCHEMBL1233547 | 0.88 | ALDH1A1 (0.67) | LMNAALDH1A1PPARDCDC25ACYP19A1 | |
| SCHEMBL4548571 | 0.88 | ALDH1A1 (0.67) | LMNAALDH1A1CDC25ASMN1; SMN2HDAC1 | |
| SCHEMBL4262388 | 0.87 | ALDH1A1 (0.67) | LMNAALDH1A1CDC25AHDAC1HDAC8 | |
| SCHEMBL6893171 | 0.87 | LMNA (1.00) | LMNAALDH1A1PPARDPPARGPPARA | |
| SCHEMBL20769719 | 0.86 | ALDH1A1 (0.65) | LMNAALDH1A1PPARDPPARGPPARA | |
| SCHEMBL13931026 | 0.85 | ALDH1A1 (0.65) | LMNAALDH1A1PPARDPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002020478-A1 | N-BENZYLINDOLE-3-ACETIC ACID DERIVATIVES FOR USE IN THE TREATMENT OF DRUG RESISTAN CANCER | DUBLIN CITY UNIVERSITY (IE) | 2002-03-14 | — | — | WO | disclosed |