Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.63 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.61 |
| ▸ | TP53 | P04637 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | UBE2N | P61088 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7696689 | 0.96 | ALDH1A1 (0.69) | ALDH1A1POLBMAPK1PTPN22MAPT | |
| SCHEMBL7697087 | 0.89 | ALDH1A1 (0.64) | ALDH1A1POLBMAPK1PTPN22MAPT | |
| SCHEMBL7669529 | 0.85 | ALDH1A1 (0.82) | ALDH1A1POLBMAPK1PTPN22MAPT | |
| SCHEMBL7694832 | 0.83 | MEN1 (0.71) | ALDH1A1POLBMAPK1PTPN22MAPT | |
| SCHEMBL7700972 | 0.83 | ALDH1A1 (0.59) | ALDH1A1POLBMAPK1PTPN22MAPT | |
| SCHEMBL7700613 | 0.81 | MAPT (0.62) | ALDH1A1MAPK1MAPTKDM4ETP53 | |
| SCHEMBL25011042 | 0.79 | ALDH1A1 (0.70) | ALDH1A1POLBMAPK1PTPN22MAPT | |
| SCHEMBL7673560 | 0.78 | TP53 (0.80) | ALDH1A1POLBMAPK1PTPN22MAPT | |
| SCHEMBL7268471 | 0.78 | MAPT (0.78) | ALDH1A1POLBMAPTKDM4ETP53 | |
| SCHEMBL7696727 | 0.78 | MAPT (0.51) | ALDH1A1POLBMAPK1PTPN22MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002100842-A1 | SULFONYLOXAZOLAMINES AND THEIR USE AS 5-HT6 LIGANDS | MERCK PATENT GMBH (DE) | 2002-12-19 | — | — | WO | disclosed |