Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Methyl Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.89 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | DNM1 | Q05193 | 9/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.46 |
| ▸ | RAD52 | P43351 | 2/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | IDE | P14735 | 1/20 | 0.39 |
| ▸ | UBE2N | P61088 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Alcohol SCHEMBL28469972 | 1.00 | LMNA (0.89) | LMNAHTTDNM1HSP90AA1RAD52 | |
| Hydrochloric Acid SCHEMBL1333871 | 0.96 | LMNA (0.96) | LMNAHTTDNM1HSP90AA1RAD52 | |
| Hydrochloric Acid SCHEMBL10580170 | 0.96 | LMNA (0.96) | LMNAHTTDNM1HSP90AA1RAD52 | |
| Hydrochloric Acid SCHEMBL33447 | 0.96 | LMNA (0.96) | LMNAHTTDNM1HSP90AA1RAD52 | |
| Hydrochloric Acid SCHEMBL1043094 | 0.96 | LMNA (0.96) | LMNAHTTDNM1HSP90AA1RAD52 | |
| Hydrochloric Acid SCHEMBL23754402 | 0.96 | LMNA (0.96) | LMNAHTTDNM1HSP90AA1RAD52 | |
| Hydrochloric Acid SCHEMBL10581679 | 0.96 | LMNA (0.96) | LMNAHTTDNM1HSP90AA1RAD52 | |
| Hydrochloric Acid SCHEMBL1123214 | 0.96 | LMNA (0.96) | LMNAHTTDNM1HSP90AA1RAD52 | |
| Hydrochloric Acid SCHEMBL10579988 | 0.96 | LMNA (0.96) | LMNAHTTDNM1HSP90AA1RAD52 | |
| Hydrochloric Acid SCHEMBL319796 | 0.96 | LMNA (0.96) | LMNAHTTDNM1HSP90AA1RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114015120-A | Antibacterial agent for plastic modification based on black phosphorus alkene and preparation method thereof | 江苏万纳普新材料科技有限公司 | 2022-02-08 | — | — | CN | claimed |
| CN-114015120-A | Antibacterial agent for plastic modification based on black phosphorus alkene and preparation method thereof | 江苏万纳普新材料科技有限公司 | 2022-02-08 | — | — | CN | disclosed |
| CN-110003919-B | Solvent-free nano-cellulose fluid and preparation method thereof | 武汉大学 | 2020-11-17 | — | — | CN | disclosed |
| US-6500552-B1 | HYDROLYSIS OF MERCAPTOALKYLSILANE COMPOUND; WEAR RESISTANCE, BONDING STRENGTH | AEG ELEKTROFOTOGRAFIE GMBH (DE) | 2002-12-31 | — | — | US | disclosed |