Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 4/20 | 0.42 |
| ▸ | HTR2C | P28335 | 5/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | PDE4A | P27815 | 3/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7696591 | 0.83 | MCHR1 (0.49) | MCHR1HTR2CHTR2APDE4APDE4B | |
| SCHEMBL7698181 | 0.83 | MCHR1 (0.49) | MCHR1HTR2CHTR2APDE4APDE4B | |
| SCHEMBL7699175 | 0.81 | MCHR1 (0.45) | MCHR1HTR2CHTR2APDE4APDE4B | |
| SCHEMBL7701165 | 0.81 | HTR2C (0.56) | MCHR1HTR2CPDE4APDE4BPDE4C | |
| SCHEMBL7700748 | 0.81 | MCHR1 (0.44) | MCHR1HTR2CHTR2APDE4APDE4B | |
| SCHEMBL7692409 | 0.80 | MCHR1 (0.44) | MCHR1HTR2CHTR2APDE4APDE4B | |
| SCHEMBL7694465 | 0.78 | MPI (0.50) | CASP3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7700309 | 0.78 | MCHR1 (0.44) | MCHR1HTR2CHTR2APDE4APDE4B | |
| SCHEMBL7692463 | 0.78 | MCHR1 (0.44) | MCHR1HTR2CHTR2APDE4APDE4B | |
| SCHEMBL7701516 | 0.78 | MCHR1 (0.42) | MCHR1HTR2CHTR2APDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002081447-A1 | 3-CYCLOPENTYLOXY-4-METHOXYPHENYL-ISOTHIAZOLINONE DERIVATIVES AND THE USE THEREOF | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2002-10-17 | — | — | WO | disclosed |