Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SNCA | P37840 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28742040 | 0.83 | SMN1; SMN2 (0.37) | ALDH1A1TSHRHSD17B10SMN1; SMN2 | |
| SCHEMBL7162982 | 0.80 | KDM4E (0.40) | ALDH1A1TSHRHSD17B10SMN1; SMN2 | |
| SCHEMBL5702291 | 0.72 | MAPK14 (0.43) | ALDH1A1 | |
| SCHEMBL27106085 | 0.71 | NPC1 (0.61) | ALDH1A1TSHRHSD17B10SMN1; SMN2 | |
| SCHEMBL15436455 | 0.71 | LMNA (0.45) | CYP3A4ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL562666 | 0.71 | ALDH1A1 (0.50) | CYP3A4ALDH1A1TSHRHSD17B10SMN1; SMN2 | |
| SCHEMBL2373096 | 0.70 | LMNA (0.44) | CYP3A4ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL209680 | 0.69 | CYP3A4 (0.70) | CYP3A4ALDH1A1TSHRHSD17B10SNCA | |
| SCHEMBL26102129 | 0.69 | LMNA (0.51) | ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL6156766 | 0.69 | KMT2A (0.45) | ALDH1A1TSHRHSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112892436-A | Full continuous flow production process of 1-alkyl-5-hydroxypyrazole | 杭州新本立医药有限公司 | 2021-06-04 | — | — | CN | disclosed |
| US-6392058-B1 | REACTING AN ALKYL VINYL ETHER WITH PHOSGENE; FORMING ACYL CHLORIDE; ESTERIFICATION; REACTING WITH HYDRAZINE | BASF AKTIENGESELLSCHAFT (DE) | 2002-05-21 | — | — | US | disclosed |
| US-6329530-B1 | REACTING ALKYL VINYL ETHER WITH PHOSGENE OR PHOSGENE DERIVATIVE TO FORM ACYL CHLORIDE DERIVATIVE; DEHYDROCHLORIANTING TO FORM 3-ALKOXYACRYLOYL CHLORIDE COMPOUND; REACTING WITH ALKYLHYDRAZINE | BASF AKTIENGESELLSCHAFT (DE) | 2001-12-11 | — | — | US | disclosed |